Studying Variation in Cancer Genomes via Whole Genome Sequencing
Semyon Kruglyak,
Director of Informatics
Illumina
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Abstract: Recent advances in sequencing technology have enabled relatively inexpensive sequencing of whole genomes. An exciting application of the technology is the sequencing and comparison of paired normal and tumor samples.
In this talk, I will provide a brief overview of the Illumina sequencing technology and describe preliminary results from a recent tumor sequencing effort. Although data collection has become straightforward, the interpretation of the data and the search for biomarkers present a significant challenge.
Presenter Biography: Semyon is the director of bioinformatics at Illumina. Since joining Illumina in 2000, he has focused on the development of the bead array platform. More recently, he has shifted his efforts to development of the sequencing technology. Before joining Illumina, he was a postdoctoral fellow in the computational biology department at the University of Southern California. Semyon received his Ph.D. in Operations Research from Cornell University in 1998. He received a BA in mathematics from Cornell in 1994.
Online Presentation: http://lifescience.planetconnect.com/ppt/PMPrinceton/SEMYON_KRUGLYAK.ppt
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