The xCELLigence System for Real-Time, Label-Free Monitoring Of Cellular Processes
Indira Carey,
Lead Field Application Scientist
Roche Diagnostics
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Abstract: The xCELLigence System allows label-free and real-time monitoring of cellular processes such as cell proliferation, cytotoxicity, adhesion, viability, invasion, and migration, using electronic cell sensor array technology. Real-time monitoring of cellular processes offers distinct and important advantages over traditional end-point assays. First, the avoidance of labels allows for more physiologically relevant assays which save on time, labor, and resources. Second, continuous monitoring over the entire course of an assay allows the user to make informed decisions regarding the timing of certain manipulations or treatments. Finally, the actual kinetic response of the cells within an assay prior or subsequent to certain manipulations provides important information regarding the biological status of the cell such as cell growth, arrest, morphological changes and apoptosis.
Presenter Biography: Dr. Indira Carey is a Lead Field Application Scientist for Roche Applied Science. In this role, Dr. Carey is responsible for introducing and supporting Roche Genomics and Cellular product solutions in the U.S. life sciences market. Prior to joining Roche, Dr. Carey held positions as a Research and Development Scientist in the Biotechnology industry where she leveraged her expertise in molecular and cellular biology for new product development.
During her academic career, Dr. Carey spear-headed gene-profiling studies in metastatic breast cancer models. She also investigated the role of B-cell specific gene expression in mouse models for autoimmune diseases such as type I diabetes and multiple sclerosis. In addition, Dr. Carey conducted research on reversing immune rejection of clotting factors in hemophilia models.
Dr. Carey is an inventor and contributor to patents on nucleic acid isolation and product related-assay improvement processes.
Online Presentation: http://lifescience.planetconnect.com/ppt/LSPrinceton/wednesday/INDIRA_CAREY.ppt
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